Problem: Which ligand binds tightest?a) ligand A, with a KL = 10E–9 Mb) ligand B, with a KL = 10E–3 Mc) ligand C, with a percent occupancy of 30% at 1 umd) ligand D, with a percent occupancy of 80% at 10 um

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Protein-Ligand Binding: a smaller value means the ligand binds tighter

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Problem Details

Which ligand binds tightest?

a) ligand A, with a KL = 10E–9 M

b) ligand B, with a KL = 10E–3 M

c) ligand C, with a percent occupancy of 30% at 1 um

d) ligand D, with a percent occupancy of 80% at 10 um