Ch.12 - Cell DivisionSee all chapters
All Chapters
Ch.1 - Introduction to Biology
Ch.2 - Chemistry
Ch.3 - Water
Ch.4 - Carbon
Ch.5 - Biological Molecules
Ch.6 - Cells
Ch.7 - The Membrane
Ch.8 - Energy and Metabolism
Ch.9 - Respiration
Ch.10 - Photosynthesis
Ch.11 - Cell Signaling
Ch.12 - Cell Division
Ch.13 - Meiosis
Ch.14 - Mendelian Genetics
Ch.15 - Chromosomal Theory of Inheritance
Ch.16 - DNA Synthesis
Ch.17 - Gene Expression
Ch.18 - Regulation of Expression
Ch.19 - Viruses
Ch.20 - Biotechnology
Ch.21 - Genomics
Ch.22 - Development
Ch.23 - Evolution by Natural Selection
Ch.24 - Evolution of Populations
Ch.25 - Speciation
Ch.26 - History of Life on Earth
Ch.27 - Phylogeny
Ch.28 - Prokaryotes
Ch.29 - Protists
Ch.30 - Plants
Ch.31 - Fungi
Ch.32 - Overview of Animals
Ch.33 - Invertebrates
Ch.34 - Vertebrates
Ch.35 - Plant Anatomy
Ch.36 - Vascular Plant Transport
Ch.37 - Soil
Ch.38 - Plant Reproduction
Ch.39 - Plant Sensation and Response
Ch.40 - Animal Form and Function
Ch.41 - Digestive System
Ch.42 - Circulatory System
Ch.43 - Immune System
Ch.44 - Osmoregulation and Excretion
Ch.45 - Endocrine System
Ch.46 - Animal Reproduction
Ch.47 - Nervous System
Ch.48 - Sensory Systems
Ch.49 - Muscle Systems
Ch.50 - Ecology
Ch.51 - Animal Behavior
Ch.52 - Population Ecology
Ch.53 - Community Ecology
Ch.54 - Ecosystems
Ch.55 - Conservation Biology

Cell Cycle Regulation

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Cell Division
Cell Cycle Regulation

Concept #1: Cell Cycle Control System

Concept #2: G2 and M Checkpoints

Concept #3: G1 Checkpoint and Cancer

Concept #4: Social Control of Cell Division

Practice: Which proteins fluctuate in concentration during the cell cycle?

Practice: Cdk stands for _____________________________________?

Practice: What proteins do cells release to stimulate other cells to divide?

Practice: Which of the following is true of cancer cells:

Practice: What is the difference between a benign tumor, and a malignant one?

Additional Problems
Normal cells are: a. anchorage dependent, density independent, division limited b. density dependent, anchorage independent, division not limited c. density dependent, anchorage dependent, division limited
By ignoring a checkpoint in the cell cycle, a cancer cell may:  a. Divide after mutations are fixed b. Divide before its DNA is completely replicated c. Condense its chromosomes before mitosis d. Align chromosomes on the equator of the cell during metaphase e. Pull chromosomes apart during anaphase
In order for a cell to become cancerous, oncogenes must be ___ and tumor suppressors ___. a. Inactivated, activatedb. Both activatedc. Both inactivatedd. Activated, inactivate
Checkpoints within the cell cycle:a. are located within interphase and allow entry to G 0b. are located within G1, S and G2c. are located within G1, M and G2d. are located within G1, M, S and G2
Replication of DNA takes place during the G1 phase of interphase.a. Trueb. False
During the cell cycle there are several checkpoints that ensure that the cell cycle is proceeding correctly. a. Trueb. False
An abnormal mass of tissue is a tumor. a. Trueb. False
If a cancer metastasizes, its cells travel through the blood stream and colonize other areas of the body.  a. True b. False
What are Check points in cell cycle?
What is cancer, why does it occur, and how do its properties evolve in humans undergoing chemotherapy?
What happens if mitosis occurs in an uncontrolled manner in the body?
In addition to Cdk1, mitosis is controlled by other kinases including polo-like kinases (PLKs). PLKs participate in mitosis by being recruited to the mitotic spindle and activated by:A. direct phosphorylation of PLKs by Cdk1B. autophosphorylationC. binding to a phosphorylated consensus sequence called polo boxes.D. binding to phosphorylated Cdk1.E. binding to cyclin.
After a protein called XrB binds to its receptor on the surface of a cell, a signal transduction pathway leads to inhibition of the cell cycle. A mutant cell line is discovered in which one of the relay proteins in the signal transduction pathway isabsent. What would be the outcome for the mutant cells?A. the cell never dividesB. the cells only divide when XrB is presentC. the cells only divide when XrB is absentD. the cells divide whether XrB is present or absent
Which one of the following statements regarding the S cyclin-CDK complex is TRUE?A. It is responsible for the phosphorylation of nuclear proteins.B. It regulates the expression of histone proteins.C. It ensures that DNA is not replicated multiple times.D. It is responsible for the degradation of nuclear membranes.E. It is regulated solely by the action of p53.
Which of the following cell cycle control system proteins are regulated by phosphorylation?A. cyclinsB. CdksC. Cdk inhibitorsD. cyclins and Cdks
What are the two proteins that regulate cell cycle?