Ch.11 - Cell SignalingSee all chapters
All Chapters
Ch.1 - Introduction to Biology
Ch.2 - Chemistry
Ch.3 - Water
Ch.4 - Carbon
Ch.5 - Biological Molecules
Ch.6 - Cells
Ch.7 - The Membrane
Ch.8 - Energy and Metabolism
Ch.9 - Respiration
Ch.10 - Photosynthesis
Ch.11 - Cell Signaling
Ch.12 - Cell Division
Ch.13 - Meiosis
Ch.14 - Mendelian Genetics
Ch.15 - Chromosomal Theory of Inheritance
Ch.16 - DNA Synthesis
Ch.17 - Gene Expression
Ch.18 - Regulation of Expression
Ch.19 - Viruses
Ch.20 - Biotechnology
Ch.21 - Genomics
Ch.22 - Development
Ch.23 - Evolution by Natural Selection
Ch.24 - Evolution of Populations
Ch.25 - Speciation
Ch.26 - History of Life on Earth
Ch.27 - Phylogeny
Ch.28 - Prokaryotes
Ch.29 - Protists
Ch.30 - Plants
Ch.31 - Fungi
Ch.32 - Overview of Animals
Ch.33 - Invertebrates
Ch.34 - Vertebrates
Ch.35 - Plant Anatomy
Ch.36 - Vascular Plant Transport
Ch.37 - Soil
Ch.38 - Plant Reproduction
Ch.39 - Plant Sensation and Response
Ch.40 - Animal Form and Function
Ch.41 - Digestive System
Ch.42 - Circulatory System
Ch.43 - Immune System
Ch.44 - Osmoregulation and Excretion
Ch.45 - Endocrine System
Ch.46 - Animal Reproduction
Ch.47 - Nervous System
Ch.48 - Sensory Systems
Ch.49 - Muscle Systems
Ch.50 - Ecology
Ch.51 - Animal Behavior
Ch.52 - Population Ecology
Ch.53 - Community Ecology
Ch.54 - Ecosystems
Ch.55 - Conservation Biology
Sections
Cell Signaling
Reception
Transduction and Response

Concept #1: G Protein Coupled Receptors and Receptor Tyrosine Kinases

Concept #2: Ligand-Gated Channels and Transcription Factors

Additional Problems
Located on or within the cell are _________ proteins, each of which has a three dimensional shape complementary to that of a specific signal molecule.a.  amplificationb.  transmembranec.  receptord.  messenger
Which of the following is likely to be a response by a receptor protein to an approaching signal molecule?a.  Recognize the receptor protein having the correct 3-D shape.b.  Receptor protein binds to signal if having complementary shape.c.  Signal binding to receptor protein induces a change in the receptor protein's shape.d.  Change in the receptor protein's shape results in cellular action.e.  All of the above are correct.
For tyrosine kinase receptors, reception is ______ and kinase activity is______.a. extracellular, intracellularb. extracellular, extracellularc. intracellular, intracellulard. intracellular, extracellular
Signal molecules activate intracellular receptors ina.  chromosomesb.  vesiclesc.  target cellsd.  skin cellse.  surface cells
The class of cell surface receptors that act indirectly on plasma membrane-bound enzymes or ion channels are calleda.  G protein coupled receptors b.  gated channelsc.  enzymic receptorsd.  second messengers 
A biochemist is designing a new drug that will mimic the shape and function of a particular signal molecule. Therefore she must produce a molecule that will bind to the receptor protein anda. induce a change in the receptor molecule shape, which will ultimately prevent a cellular response.b. induce a change in the receptor molecule shape, which will ultimately produce a cellular response.c. produce a cellular response by altering the Na+/K+ pump located near the receptor site.
Chemically-gated ion channels are receptor proteins through which ions pass. A cell biologist has blocked these channels in a lab rat's liver tissue by using a chemical thata. prohibits binding of a signal molecule.b. prohibits ions from entering the cell via active transport.c. causes ions to move in the opposite direction of the ion gradient.d. prohibits second messenger signaling.
G-protein-coupled receptors are the largest family of cell surface receptors. Each receptor passes through the plasma membranea. three times.b. four times.c. five times.d. six times.e. seven times.
What characteristics do all cell surface receptors share?a. They are composed of hydrophilic proteins.b. They all must bind to a molecule to be activated.c. They all result in creation of an ion channel.d. They include the activation of a G protein.
You are planning to perform some protein-protein interaction studies to identify a receptor for a steroid hormone you have been working on. With which of the following types of cell extracts should you begin?a. Plasma membraneb. Extracellularc. Cytoplasmicd. Nuclear
A mutation in the DNA binding domain of a steroid hormone receptor is most likely to affect thea. Conformational change of the receptor.b. Binding of the hormone to the receptor.c. Translocation of the receptor to the nucleus.d. Cellular response to the hormone.
Vasopressin is a hormone that is primarily released when the body is low on water. Release of vasopressin causes the kidneys to conserve water by concentrating urine and decreasing urine output. However, vasopressin also has additional functions in other tissues such as the brain and blood vessels, which are not directly involved in urine production. How could it be possible for vasopressin to trigger different responses in different tissues?a. Vasopressin can bind to, and act on, different receptor subtypes, leading to different cellular responses in different tissues.b. Vasopressin can be released at different times to result in different effects.c. Because vasopressin is a hormone, it can be sent to specific regions of the body leading to specific effects
The binding of a catecholamine to a beta adrenergic receptor will ________.a. activate guanylate cyclaseb. inhibit guanylate cyclasec. activate adenylate cyclased. inhibit phospholipase Ce. activate phospholipase C
What is the immediate result of a signal binding to a receptor?A. cellular movementB. Altered DNA useC. conformational change of the receptorD. release of IP3