The translation process basically starts with the start codon of the mRNA. It also determines the reading frame that establishes the succeeding codons. Mutations that lead to either insertions or deletions result in a shift in the reading frame, causing a cascade of changes in the amino acids encoded by the sequence.
The mRNA sequence belowcodes for part of a protein. The reading frame for the translation of this mRNA starts with the first three nucleotides as shown.
Met Arg Ser Glu Pro Arg Asp Lys His
A. What would be the consequence of the insertion of an A after the third nucleotide of the sequence?
B. What would be the consequence of the deletion of the C at the beginning of this sequence?
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