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Problem: A single base substitution is LEAST likely to be deleterious (dangerous) when the change results in _____.A. the replacement of a codon specifying a hydrophilic amino acid with a codon that specifies a hydrophobic amino acid.B. the replacement of a codon specifying an amino acid with a stop codon.C. the substitution of an amino acid in the active site of the protein.D. the replacement of a codon specifying an amino acid with a different codon that specifies the same amino acid.

FREE Expert Solution

The effect of a particular mutation, be it a substitution, deletion, or insertion, largely depends on the changes in the coding regions of DNA sequence, leading to modifications in the translated protein sequence.

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Problem Details

A single base substitution is LEAST likely to be deleterious (dangerous) when the change results in _____.

A. the replacement of a codon specifying a hydrophilic amino acid with a codon that specifies a hydrophobic amino acid.

B. the replacement of a codon specifying an amino acid with a stop codon.

C. the substitution of an amino acid in the active site of the protein.

D. the replacement of a codon specifying an amino acid with a different codon that specifies the same amino acid.

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What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Mutation concept. You can view video lessons to learn Mutation. Or if you need more Mutation practice, you can also practice Mutation practice problems.

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Based on our data, we think this problem is relevant for Professor Firooznia's class at CCNY.