Solution: Suppose that rat liver expresses a protein called Yorfavase. The enzyme is composed of 192 amino acid residues, and thus the coding region of the yfg gene consists of 576 bp. However, the rat genome database indicates that the yfg gene consists of 1440 bp.Select which type of DNA does not contribute to the additional 864 bp found in the yfg gene.A. 5'-end untranslated regulatory region.B. centromeric DNAC. DNA coding for a signal sequenceD. noncoding intronE. promoter sequence

Problem

Suppose that rat liver expresses a protein called Yorfavase. The enzyme is composed of 192 amino acid residues, and thus the coding region of the yfg gene consists of 576 bp. However, the rat genome database indicates that the yfg gene consists of 1440 bp.

Select which type of DNA does not contribute to the additional 864 bp found in the yfg gene.

A. 5'-end untranslated regulatory region.

B. centromeric DNA

C. DNA coding for a signal sequence

D. noncoding intron

E. promoter sequence

Solution

The gene sequence is usually known to be the reference for protein synthesis as they are used to provide the codon sequences through mRNA. However, in eukaryotes, it is not the whole RNA product that will be used for translation. There are regions, known as noncoding sequences, that are not converted to an amino acid sequence but have other functions.

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