The general transcription factors (GTFs) are the class of transcription factors that bind to different sites to activate transcription. The relatively high number of available transcription factors are used in different stages of transcription. For example, around five transcription factors form a closed complex that assists in the unwinding of DNA.
Which is NOT a function of general transcription factors?
A. recruitment and binding of RNA polymerase to promoters
B. melting of the DNA helix to expose template
C. escape of the polymerase from the promoter
D. termination of transcription