As organisms evolve, the proteins that they use in performing different functions are also modified, as well. The eveolution of these organisms give rise to homologous genes, which lead to the formation of homologous proteins. Homologous proteins are a pair of proteins that are similar in structure. The DNA sequence resulting to these proteins are considered to have shared ancestry. This may be due to either a speciation event, thereby producing orthologs, or gene duplication and divergence, resulting in paralogs.
Choose the correct statements about proteins and evolution. Select all that apply.
A. Two proteins that have similar tertiary structure are said to be homologous.
B. The tertiary structure of a protein is more conserved than the primary structure.
C. Lupine leghemoglobin and human α-hemoglobin are only about 16% identical. This is an example of divergent evolution.
D. Orthologs are derived from a common ancestor, but often have different functions.
E. Percent identity for a random alignment of two nucleic acids is likely to be lower than the percent identity for an equal-length random alignment of two polypeptide segments.
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