Tumors are known to develop and patient condition worsen with time. However, this does not actually show the multi-step progression of cancer. It can only suggest that a number of processes might have been completed leading to cancer. However, cancer is known to have started mainly with tumors.
Cancer is considered a progressive multi-step disease, why is this?
A. Tumor development arises from the accumulation of 4-6 different mutations in cells over the course of many years.
B. Tumors development spreads to other tissue with time.
C. Tumor development requires mutations in the affected cells as well as defects in the immune system.
D. Tumor development happens in a step-wise fashion as telomeres shorten with each cell division.
E. Tumor development gets worse with time.
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