DNA Replication Video Lessons

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Problem: Below is a close-up of the portion ofaDNA replication bubble found in the highlighted box. Helicase is shown as a green triangle currently moving from left to right. Based on what you know about the creation of new DNA during replication, which is the lagging strandand why? A. A is the lagging strand, as DNA is always synthesized in the 5' to 3' manner.B. B is the lagging strand, as DNA is always synthesized in the 5' to 3' manner.C. A is the lagging strand, as DNA is always synthesized in the 3' to 5' manner.D. B is the lagging strand, as DNA is always synthesized in the 3' to 5' manner.E. It is impossible to tell, with the information provided.

FREE Expert Solution

The objective of DNA replication is to create a new copy of the double stranded polynucleotide strand. This follows a semi-conservative mechanism of synthesis where the parent nucleotide strand is opened up from the origin of replication, and the complementary strand is synthesized with the help of the DNA polymerase enzyme, using the primers as the starting point of base synthesis. This copying mechanism has a high degree of sequence conservation as the DNA polymerase has a proofreading and correcting function, as well.

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Problem Details

Below is a close-up of the portion ofaDNA replication bubble found in the highlighted box. Helicase is shown as a green triangle currently moving from left to right. Based on what you know about the creation of new DNA during replication, which is the lagging strandand why? 

A. A is the lagging strand, as DNA is always synthesized in the 5' to 3' manner.

B. B is the lagging strand, as DNA is always synthesized in the 5' to 3' manner.

C. A is the lagging strand, as DNA is always synthesized in the 3' to 5' manner.

D. B is the lagging strand, as DNA is always synthesized in the 3' to 5' manner.

E. It is impossible to tell, with the information provided.

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What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the DNA Replication concept. You can view video lessons to learn DNA Replication. Or if you need more DNA Replication practice, you can also practice DNA Replication practice problems.

What professor is this problem relevant for?

Based on our data, we think this problem is relevant for Professor Navaratnam's class at WVU.