Remember that RNA polymerase can only synthesize a polynucleotide strand in the 5' to 3' direction. In addition to this, the complementary base pairing happens in an antiparallel manner.
Which of the following is correct about the synthesis of RNA during transcription?
A. It proceeds in a 5' to 3' direction, antiparallel to the sense (non-template) strand.
B. It proceeds in a 5' to 3' direction, antiparallel to the antisense (template) strand.
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