Problem: A. What is the ΔGº' for the reaction below, given that the ΔGº' for ATP hydrolysis to ADP is -30.5 kJ/mol and the ΔGº' for the hydrolysis of 1,3-bisphosphoglycerate to 3-phosphoglycerate is -49.4 kJ/mol?1,3-bisphosphoglycerate + ADP → 3-phosphoglycerate + ATPB. What is the equilibrium constant for this reaction?

FREE Expert Solution

The given reaction is a coupled reaction of ADP phosphorylation and 1,3-bisphosphoglycerate hydrolysis. This is actually the 7th reaction in glycolysis and the first ATP-forming reaction.

For a coupled reaction, the total change in free energy is the sum of the free energy change of individual reactions. In addition to this, for an individual reversible reaction, the reversed reaction will just have the negative free energy change of the initial given reaction.

View Complete Written Solution
Problem Details

A. What is the ΔGº' for the reaction below, given that the ΔGº' for ATP hydrolysis to ADP is -30.5 kJ/mol and the ΔGº' for the hydrolysis of 1,3-bisphosphoglycerate to 3-phosphoglycerate is -49.4 kJ/mol?

1,3-bisphosphoglycerate + ADP → 3-phosphoglycerate + ATP

B. What is the equilibrium constant for this reaction?

Frequently Asked Questions

What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Gibbs Free Energy concept. If you need more Gibbs Free Energy practice, you can also practice Gibbs Free Energy practice problems.