The given reaction is a coupled reaction of ADP phosphorylation and 1,3-bisphosphoglycerate hydrolysis. This is actually the 7th reaction in glycolysis and the first ATP-forming reaction.
For a coupled reaction, the total change in free energy is the sum of the free energy change of individual reactions. In addition to this, for an individual reversible reaction, the reversed reaction will just have the negative free energy change of the initial given reaction.
A. What is the ΔGº' for the reaction below, given that the ΔGº' for ATP hydrolysis to ADP is -30.5 kJ/mol and the ΔGº' for the hydrolysis of 1,3-bisphosphoglycerate to 3-phosphoglycerate is -49.4 kJ/mol?
1,3-bisphosphoglycerate + ADP → 3-phosphoglycerate + ATP
B. What is the equilibrium constant for this reaction?
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