It can be seen from the pedigree that the disease is transmitted as an autosomal recessive. The parents of individuals 1-3 are both unaffected but they had children who are affected. That makes these parents both heterozygous. But despite knowing their genotypes, we still cannot be definite with the genotype of individual 2.
Look at the pedigree below. Let's say that individual 2 has achild with a man who does not have the disease and is not a carrier (FF). What are the results of their cross? Do a Punnet Square.
A. 50% Ff, 50% F?
B. 50% FF, 50% F?
C. 50% FF, 50% Ff
D. We cannot determine this because we don't know the genotype of individual 2.
Frequently Asked Questions
What scientific concept do you need to know in order to solve this problem?
Our tutors have indicated that to solve this problem you will need to apply the Genetic Counseling concept. You can view video lessons to learn Genetic Counseling. Or if you need more Genetic Counseling practice, you can also practice Genetic Counseling practice problems.
What professor is this problem relevant for?
Based on our data, we think this problem is relevant for Professor Reece's class at CSU.