The p53 is a known tumor-suppressor gene as its normal protein product promotes the synthesis of proteins that inhibit cell cycle. Other than this particular function, there are also other pathways for tumor suppression, such as DNA damage repair and cell adhesion control. Its deactivation therefore, will lead to uncontrolled cell division as no signal will be made to stop it.
What will happen if a p53 mutation occurs that prevents p53 phosphorylation?
A. promote cancer development
B. prevent cancer development
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