The translation of mRNA transcript to a polypeptide sequence follows a specific set of simple guidelines. Most of these revolve on three-base RNA sequences known as codons. The first is the determination of the start codon and the reading frame. The codon that signals the start of translation within a sequence is AUG. This also determines the reading frame, or how the sequence is divided into codons for translation. For example, since the mRNA transcript starts with AUG, if grouped into codons, the sequence would look like this:
Translate the following sequence:
A. Mat Gly Tyr Val Ser Thr Arg Phe Ser Leu His Gly Gly Ala His Ile
B. Met Gly Tyr Val Ser Thr Arg Phe Ser Glu Pro
C. Met Gly Tyr Ile Gln Glu Pro Thr
D. Met Gly Tyr Ile Gln Val Thr Arg Arg Ser Pro His
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