Problem: A cell goes through the stages of cellular respiration but upon reaching oxidative phosphorylation it cannot generate ATP. What are two possible reasons that could account for this result and explain WHY?

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During cellular respiration, once cell reached the oxidative phosphorylation, it cannot generate ATP due to the following possible reasons:

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A cell goes through the stages of cellular respiration but upon reaching oxidative phosphorylation it cannot generate ATP. What are two possible reasons that could account for this result and explain WHY?