Biology Practice Problems Proteins Practice Problems Solution: Which of the following bonds or interactions is/ar...

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Solution: Which of the following bonds or interactions is/are possible contributors to the stability of the tertiary structure of a globular protein?A. Peptide bonds between a metal ion cofactor and a histidine residueB. Hydrophobic interactions between histidine and tryptophan R groups.C. Covalent disulfide cross-links between 2 methionine residues.D. Hydrogen bonds between serine residues and the aqueous surroundings.E. All of the above contribute.

Problem

Which of the following bonds or interactions is/are possible contributors to the stability of the tertiary structure of a globular protein?

A. Peptide bonds between a metal ion cofactor and a histidine residue

B. Hydrophobic interactions between histidine and tryptophan R groups.

C. Covalent disulfide cross-links between 2 methionine residues.

D. Hydrogen bonds between serine residues and the aqueous surroundings.

E. All of the above contribute.

Solution

The tertiary structure of a protein is define as the 3-D structure formed by the polypeptide chain due to the numerous interactions that the sequence can have with itself and its environment including hydrophobic interactions and H-bonding.

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