Hardy-Weinberg Model Video Lessons

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Problem: The genotypic frequencies of the MN blood groups in various populations are shown below. Given this information, determine if the genotypic frequencies are in general agreement with the Hardy-Weinberg law.

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For the population of U.S. whites, relative genotype frequency for MM is 0.29, and for NN is 0.23. The relative frequencies of p and q are therefore, 0.539 (from √0.29) and 0.480 (from √0.23). Aside from the fact that p and q do not sum up to 1, their product multiplied by 2 is not equivalent to the relative genotypic frequency of the heterozygous group. Thus, it is not in agreement with the Hardy-Weinberg equilibrium.

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Problem Details

The genotypic frequencies of the MN blood groups in various populations are shown below. Given this information, determine if the genotypic frequencies are in general agreement with the Hardy-Weinberg law.

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