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Problem: Alpers' disease is a mitochondrially inherited disease with symptoms that include seizures, dementia, blindness, liver dysfunction, and cerebral degeneration. The pedigree below shows the presence of Alpers' disease in three generations. Individual 4had one daughter and two sons, and individual 6 had two daughters and one son.Which of the individuals indicated below are affected by Alpers' disease? Place the correct symbols on the pedigree showing affected and unaffected individuals.

FREE Expert Solution

The individual in II-5 can either be a male or a female, but definitely, he/she is affected with Alpers' disease. The complete pedigree for the three generations is shown below (II-5 will be shown as male for this illustration):

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Problem Details

Alpers' disease is a mitochondrially inherited disease with symptoms that include seizures, dementia, blindness, liver dysfunction, and cerebral degeneration. The pedigree below shows the presence of Alpers' disease in three generations. Individual 4had one daughter and two sons, and individual 6 had two daughters and one son.

Which of the individuals indicated below are affected by Alpers' disease? Place the correct symbols on the pedigree showing affected and unaffected individuals.

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What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Genetic Counseling concept. You can view video lessons to learn Genetic Counseling. Or if you need more Genetic Counseling practice, you can also practice Genetic Counseling practice problems.

What professor is this problem relevant for?

Based on our data, we think this problem is relevant for Professor Bekker's class at UCF.