Biology Practice Problems Mutation Practice Problems Solution: In the strand below, a mutation occurs at the 8th ...

Solution: In the strand below, a mutation occurs at the 8th nucleotide. The nucleotide is deleted. Transcribe then translate the strand to see what happens to the protein.original : 3' - TAG CTG AAT TGC AGT GCC ATC GATG - 5'mutated : 3' - TAG CTG ATT GCA TTG CCA TTG ATG - 5'

Problem

In the strand below, a mutation occurs at the 8th nucleotide. The nucleotide is deleted. Transcribe then translate the strand to see what happens to the protein.

original : 3' - TAG CTG AAT TGC AGT GCC ATC GATG - 5'

mutated : 3' - TAG CTG ATT GCA TTG CCA TTG ATG - 5'

Solution

Remember that transcription is a process that produces an RNA copy of the genetic information found in the DNA prior to its expression. This uses an RNA polymerase for the creation of the DNA's complementary RNA strand, known as mRNA.

Just like the DNA polymerase, the RNA polymerase synthesizes the complementary strand in a 5' to 3' direction. It starts at the 3' end of the DNA and begins the pairing up of bases just like the complementary base pairing in double-stranded DNA. The only exception for this is that the RNA polymerase pairs up the A of the DNA with a corresponding U for the RNA strand.

Thus, for the problem, the products of transcription will be:

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