Chromosome Abnormalities and Non-Mendelian Inheritance Video Lessons

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Problem: Consider the effects of a mutation in humans that reduces the accuracy of the meiotic divisions that give rise to gametes. What predictions can be made about a woman that is homozygous for such a mutation?A. Most of her children will be boys.B. Among her children, the frequency of Down's syndrome will be increased compared to the population as a whole.C. Her children will be taller than average.D. Among her children, the frequency of XYY male children will be increased compared to the population.E. Both answers B and D are correct.

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The gametes that are produced during meiotic divisions are the ones that will be passed on their offspring. Having a mutation on genes that can affect the accuracy of meiosis could potentially increase the occurrence of errors during gamete formation.

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Problem Details

Consider the effects of a mutation in humans that reduces the accuracy of the meiotic divisions that give rise to gametes. What predictions can be made about a woman that is homozygous for such a mutation?

A. Most of her children will be boys.

B. Among her children, the frequency of Down's syndrome will be increased compared to the population as a whole.

C. Her children will be taller than average.

D. Among her children, the frequency of XYY male children will be increased compared to the population.

E. Both answers B and D are correct.

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