Problem: Once a substance is engulfed into cells, which structure determine their fate? What happens if it is a toxic or bact debris?

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The fate of the substance that were engulfed in a cell through endocytosis is and can be determined by the endocytotic pathways. There are four endocytosis pathway namely: 

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Once a substance is engulfed into cells, which structure determine their fate? What happens if it is a toxic or bact debris?

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