This would simply make use of the Nernst equation.
R is the universal gas constant, 8.314 J/mol K
T is the absolute temperature for the system, that is 37ºC for cells (310 K)
z is the charge of the ion (+2)
F is Faraday's constant (96485 C/mol e)
[Ca+2]out and [Ca+2] in would be the molar concentration of Ca+2 outside and inside of the cell, respectively.
If Ca+2 concentrations inside and outside a cell are 10-7 and 10-3 M, respectively, then ECa+2 will be:
a. +61.5 mV
b. +246 mV
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