Mutation Video Lessons

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Problem: Given the DNA sequences below of coding strands, identify and underline the mutation in each. What effect did each DNA mutation have on the final protein products. What type of mutation occurred (synonymous, non-synonymous, nonsense, nonstop)? Explain. Original DNA Sequence5’ – A T G T T T C T G G T C A A T T G C G C A G G T C C A A C C T A G – 3’Mutated Sequences:A. 5’ – A T G T T T T T G G T C A A T T G C G C A G G T C C A A C C T A G – 3’B. 5’ – A T G T T T G T G G T C A A T T G C G C A G G T C C A A C C T A G – 3’C. 5’ – A T G T T T C T G G T C A A T T G C G C A G G T C C A A C C T A A – 3’D. 5’ – A T G C T T T C T G G T C A A T T G C G C A G G T C C A A C C T A G – 3’E. 5’ – A T G T T T C T G G T C A A T T A G C G C A G G T C C A A C C T A G – 3’F. Which of the above mutations do you think would be more deleterious to the cell/organism? Explain your reasoning. 

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Problem Details

Given the DNA sequences below of coding strands, identify and underline the mutation in each. What effect did each DNA mutation have on the final protein products. What type of mutation occurred (synonymous, non-synonymous, nonsense, nonstop)? Explain. Original DNA Sequence

5’ – A T G T T T C T G G T C A A T T G C G C A G G T C C A A C C T A G – 3’

Mutated Sequences:

A. 5’ – A T G T T T T T G G T C A A T T G C G C A G G T C C A A C C T A G – 3’

B. 5’ – A T G T T T G T G G T C A A T T G C G C A G G T C C A A C C T A G – 3’

C. 5’ – A T G T T T C T G G T C A A T T G C G C A G G T C C A A C C T A A – 3’

D. 5’ – A T G C T T T C T G G T C A A T T G C G C A G G T C C A A C C T A G – 3’

E. 5’ – A T G T T T C T G G T C A A T T A G C G C A G G T C C A A C C T A G – 3’

F. Which of the above mutations do you think would be more deleterious to the cell/organism? Explain your reasoning. 

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What scientific concept do you need to know in order to solve this problem?

Our tutors have indicated that to solve this problem you will need to apply the Mutation concept. You can view video lessons to learn Mutation. Or if you need more Mutation practice, you can also practice Mutation practice problems.

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Our expert Biology tutor, Kaitlyn took 36 minutes and 6 seconds to solve this problem. You can follow their steps in the video explanation above.