Bacterial Gene Regulation Video Lessons

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Problem: Describe the two ways in which the amino acid tryptophan regulates expression of the trp operon in E. coli.

FREE Expert Solution

Expression of the operon is regulated through:

  • Repression. Expression or trp operon would not be initiated without the presence of tryptophan. Without the presence of the amino acid, RNA Polymerase would bind to the DNA and would eventually be transcribed. However, with the presence of tryptophan, trp repressor would bind to the DNA of trp operon, blocking the way for RNA Polymerase. Thus, tryptophan is usually coined to as a corepressor. 
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Problem Details

Describe the two ways in which the amino acid tryptophan regulates expression of the trp operon in E. coli.

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