Problem: Explain the role of release factors in transcription termination.
FREE Expert Solution
A release factor is a protein that allows for the termination of translation by recognizing the termination codon or stop codon in an mRNA sequence. There are multiple proteins that recognizes different stop codons.
In prokaryotic transcriptional termination, there are three release factors.
- RF1 recognizes the termination codons UAA and UAG
- RF2 recognizes UAA and UGA
- RF3 is a GTP-binding protein that leads to the dissociation of RF1/RF2 after peptide release
Problem Details
Explain the role of release factors in transcription termination.
Frequently Asked Questions
What scientific concept do you need to know in order to solve this problem?
Our tutors have indicated that to solve this problem you will need to apply the Transcription concept. You can view video lessons to learn Transcription. Or if you need more Transcription practice, you can also practice Transcription practice problems.
What professor is this problem relevant for?
Based on our data, we think this problem is relevant for Professor Halpin's class at NYU.