In eukaryotes, general transcription factors:
a. inhibit RNA polymerase binding to the promoter and begin transcribing.
b. bind to other proteins or to a sequence element within the promoter called the TATA box.
c. bind to sequences just after the start site of transcription.
d. usually lead to a high level of transcription even without additional specific transcription factors.
e. are required for the expression of specific protein-encoding genes.
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