Biology Practice Problems Mutation Practice Problems Solution: How do splice-site mutations differ from nonsense ...

Solution: How do splice-site mutations differ from nonsense mutations?

Problem

How do splice-site mutations differ from nonsense mutations?

Solution

Mutations during splicing may lead to different consequences depending on how the mutation occurred. These mutations may happen through insertion, deletion and frameshift. For example, deletion of the splicing site will lead to extra introns remaining in the mature mRNA which will result to abnormal protein production.

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