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Problem: Explain why deletion of a single nucleotide in a gene generally results in more severe defects in the polypeptide than a point mutation that changes a single nucleotide.

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Deletion of a single nucleotide in a gene may result to severe defects in polypeptide than a point mutation in a single nucleotide.

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Problem Details

Explain why deletion of a single nucleotide in a gene generally results in more severe defects in the polypeptide than a point mutation that changes a single nucleotide.

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What scientific concept do you need to know in order to solve this problem?

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Based on our data, we think this problem is relevant for Professor Roehrig's class at HARVARD.