Mutation Video Lessons

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Problem: Which point mutation would be most likely to have a catastrophic effect on the functioning of a protein? a. a base substitution b. a base deletion near the start of the coding sequence c. a base deletion near the end of the coding sequence, but not in the terminator codon d. deletion of three bases near the start of the coding sequence, but not in the initiator codon e. a base insertion near the end of the coding sequence, but not in the terminator codon

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Problem Details

Which point mutation would be most likely to have a catastrophic effect on the functioning of a protein?

a. a base substitution

b. a base deletion near the start of the coding sequence

c. a base deletion near the end of the coding sequence, but not in the terminator codon

d. deletion of three bases near the start of the coding sequence, but not in the initiator codon

e. a base insertion near the end of the coding sequence, but not in the terminator codon

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Based on our data, we think this problem is relevant for Professor Parks' class at NCSU.