Autosomal Inheritance

Use the pedigree diagram below to answer the following question. Blue toes is an autosomal recessive trait.What is the genotype of the female in generation I?

A healthy young couple are both carriers of cystic fibrosis, the chance that each of their future children will inherit this serious illness is:  a. 0%, because cystic fibrosis is not an inherited illness b. 25% c. 10% d. 50% e. 100%

To inherit an autosomal dominant disorder a person could receive the disease causing allele from:  a. The father only, not the mother b. The mother only, not the father c. The mother or the father d. The parent who does not exhibit the disease e. All are correct

To inherit an autosomal recessive disorder requires a person to receive the disease causing allele from:  a. The father only b. The mother only c. Only the parent having the disease d. Only one parent who is homozygous recessive for the disease e. Both parents

If a person has a recessive allele for a disease and that allele is masked by a normal dominant allele, this person:  a. Homozygous for the disease b. Cannot produce gametes c. Is termed a "carrier" d. Is termed a linkage group e. Has the disease but cannot pass this disease to their offspring

In pedigree charts, autosomal dominant disorders typically:  a. Appear only in males b. Appear only in females c. Appear in every generation d. Seem to disappear in one generation, only to reappear in the next generation e. Occur every third generation

In pedigree charts, autosomal recessive disorders typically:  a. Appear in every generation b. Appear only in males c. Appear only in females d. Seem to disappear in one generation, only to reappear in the next generation e. Occur every third generation

In cystic fibrosis, two unaffected carriers can have a child with the disease. It is as common in boys as in girls. This disease is:  a. Autosomal dominant b. X-linked recessive c. Autosomal recessive d. X-linked dominant e. Pleiotropic

In Huntington disease, a child will typically only get the disease if one parent also has it. It is as common in boys as in girls. This disease is:  a. Autosomal recessive b. X-linked recessive c. X-linked dominant d. Autosomal dominant e. Pleiotropic

The following pedigree shows the presence of individuals bearing extra fingers and toes--exhibiting "polydactyly." Explain the genetic mechanism for the inheritance of this trait in the family.

Assume that in cats, a crooked tail is caused by an autosomal recessive allele. A male and female cat, each with normal tails, have previously had a litter of kittens in which some kittens had crooked tails. What is the probability that the same two parents will next produce two normal females or two males with crooked tails?a. 5/8b. 9/16c. 9/32d. 9/64e. 5/32

If the shaded phenotype in the pedigree above is caused by an autosomal dominant allele, then what is the chance that individuals labeled 4 & 5 (in row II) will have an unafflicted (unshaded) daughter?a. 100%b. 25%c. 50%d. 75%e. it cannot be determined from the information provided

Which of the following is LEAST likely to be a health problem for someone with cystic fibrosis?a. nutritional deficienciesb. diabetesc. frequent infectionsd. obesityThe allele that causes cystic fibrosis is recessive. An individual who is heterozygous for cystic fibrosisa. is a carrier.b. cannot reproduce.c. will have children who are all carriers of cystic fibrosis.d. cannot have children with cystic fibrosis.Sophie has cystic fibrosis. If Sophie conceives a child, and the father neither has cystic fibrosis nor is a carrier, what are the chances that the child would have cystic fibrosis?a. 25%, because only one in four gametes will carry the bad geneb. 50%, because there is a 50% chance that Sophie will pass along the bad genec. 100%, because Sophie has the conditiond. 75%, because Sophie has the condition but the father does note. 0%, because the child must receive the bad gene from both parentsSophie's parents are carriers for cystic fibrosis. If Sophie has a brother or sister from the same parents, what are the chances that the sibling would have cystic fibrosis?a. 50%b. 100%c. 75%d. 25%e. 0%