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Ch. 11 - Biological Membranes and Transport WorksheetSee all chapters

# Thermodynamics of Membrane Diffusion: Charged Ion

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Sections
Biological Membrane Transport
Passive vs. Active Transport
Passive Membrane Transport
Facilitated Diffusion
Erythrocyte Facilitated Transporter Models
Membrane Transport of Ions
Primary Active Membrane Transport
Sodium-Potassium Ion Pump
SERCA: Calcium Ion Pump
ABC Transporters
Secondary Active Membrane Transport
Glucose Active Symporter Model
Endocytosis & Exocytosis
Neurotransmitter Release
Summary of Membrane Transport
Thermodynamics of Membrane Diffusion: Uncharged Molecule
Thermodynamics of Membrane Diffusion: Charged Ion

Concept #1: Thermodynamics of Membrane Diffusion: Charged Ion

Example #1: Calculate the energy cost of pumping Calcium from the cytosol to the extracellular space:

Practice: Calculate the free energy change (ΔG transport) for the movement of Na + into a cell when its concentration outside is 150 mM and its cytosolic concentration is 10 mM. Assume that T = 20°C and ΔΨ = –50 mV (inside negative).

Practice: Calculate the ΔGtransport required to move 1 mole of Na + ions from inside the cell ([Na+] inside = 5 mM) to the outside of the cell ([Na +] outside = 150 mM) when ΔΨ = –70 mV (inside negative) & the temperature is 37°C.

Practice: Calculate the ΔGtransport when Ca2+ ions move from the endoplasmic reticulum ([Ca2+] = 1 mM) to the cytoplasm ([Ca2+] = 0.1 μM). Assume that ΔΨ = 0 and T = 25°C.