Concept #1: Introduction to Rate Constants

Concept #2: Types of Rate Constants

Practice: Which of the following rate constants is negligible for the initial velocity (V _{0}) of an enzyme-catalyzed reaction?

Concept #3: Rate Law: Calculating Reaction Rate (v) with Rate Constant (k)

Practice: Calculate the reaction rate for the following simple reaction if k = 1.3 x 10 ^{-1} M^{-1}s^{-1}, initial [A] = 4.0 x 10^{-3} M, and the initial [B] = 6.0 x 10 ^{-3} M (for simple reactions, assume coefficients are reaction orders):

**A + B → 2C**

Concept #4: Rate Laws for Enzyme-Catalyzed Reactions

Practice: Write out the rate law equations for each association/dissociation indicated below.

a) Rate law for ES dissociation into E + P: V = ______________

b) Rate law for E + S association: V = ______________

c) Rate law for ES dissociation back into E + S: V = ______________

Practice: In a typical enzyme-catalyzed reaction, when & why is the rate constant k _{-2} negligible?