Ch. 4 - Protein StructureWorksheetSee all chapters
All Chapters
Ch. 1 - Introduction to Biochemistry
Ch. 2 - Water
Ch. 3 - Amino Acids
Ch. 4 - Protein Structure
Ch. 5 - Protein Techniques
Ch. 6 - Enzymes and Enzyme Kinetics
Ch. 7 - Enzyme Inhibition and Regulation
Ch. 8 - Protein Function
Ch. 9 - Carbohydrates
Ch. 10 - Lipids
Ch. 11 - Biological Membranes and Transport
Ch. 12 - Biosignaling
Clutch Review 1: Nucleic Acids, Lipids, & Membranes
Clutch Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Clutch Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism
Clutch Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Sections
Peptide Bond
Primary Structure of Protein
Altering Primary Protein Structure
Drawing a Peptide
Determining Net Charge of a Peptide
Isoelectric Point of a Peptide
Approximating Protein Mass
Peptide Group
Ramachandran Plot
Atypical Ramachandran Plots
Alpha Helix
Alpha Helix Pitch and Rise
Alpha Helix Hydrogen Bonding
Alpha Helix Disruption
Beta Strand
Beta Sheet
Antiparallel and Parallel Beta Sheets
Beta Turns
Tertiary Structure of Protein
Protein Motifs and Domains
Denaturation
Anfinsen Experiment
Protein Folding
Chaperone Proteins
Quaternary Structure
Simple Vs. Conjugated Proteins
Fibrous and Globular Proteins

Concept #1: Phi, Psi & Omega Bonds

Practice: Which of the following pairs of peptide-backbone bonds show free rotation around both bonds?

Concept #2: Ramachandran Plot

Practice: A Ramachandran plot shows:

Practice: Why are some regions of a Ramachandran plot shaded while others are unshaded? Circle all true answers.

Practice: The predominate structure in α-keratin, a mammalian protein that makes up large portions of hair & nails, is the α-helix. Mark the approximate locations on a Ramachandran plot you might expect to find φ and ψ angles for α-keratin amino acid residues.

Practice: The principal component of silk is the protein fibroin, which is a classic example of β-sheet structure. Mark the approximate locations on a Ramachandran plot you might expect to find φ and ψ angles for silk amino acid residues.

Practice: Which of the following statements is true for the portion of the peptide shown in the figure below?