Ch. 12 - BiosignalingWorksheetSee all chapters
All Chapters
Ch. 1 - Introduction to Biochemistry
Ch. 2 - Water
Ch. 3 - Amino Acids
Ch. 4 - Protein Structure
Ch. 5 - Protein Techniques
Ch. 6 - Enzymes and Enzyme Kinetics
Ch. 7 - Enzyme Inhibition and Regulation
Ch. 8 - Protein Function
Ch. 9 - Carbohydrates
Ch. 10 - Lipids
Ch. 11 - Biological Membranes and Transport
Ch. 12 - Biosignaling
Clutch Review 1: Nucleic Acids, Lipids, & Membranes
Clutch Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Clutch Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism
Clutch Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Introduction to Biosignaling
G protein-Coupled Receptors
Stimulatory Adenylate Cyclase GPCR Signaling
Inhibitory Adenylate Cyclase GPCR Signaling
Drugs & Toxins Affecting GPCR Signaling
Recap of Adenylate Cyclase GPCR Signaling
Phosphoinositide GPCR Signaling
PSP Secondary Messengers & PKC
Recap of Phosphoinositide Signaling
Receptor Tyrosine Kinases
Insulin Receptor
Insulin Signaling on Glucose Metabolism
Recap Of Insulin Signaling in Glucose Metabolism
Insulin Signaling as a Growth Factor
Recap of Insulin Signaling As A Growth Factor
Recap of Insulin Signaling
Jak-Stat Signaling
Lipid Hormone Signaling
Summary of Biosignaling
Signaling Defects & Cancer

Concept #1: Phosphoinositide GPCR Signaling

Concept #2: 3 Phosphoinositide Secondary Messengers

Practice: Which of the following are secondary messengers produced in the PSP pathway?

Concept #3: Signaling Pathway 

Concept #4: How to Remember Phosphoinositide GPCR Signaling?

Example #1: Place the following steps of the PSP signaling pathway in order from 1-7:

Practice: When epinephrine binds to a(n) ________________ receptor, _______ is activated, causing an increase in the cellular concentration of ________________.

Practice: Which of the following secondary messengers, when released by phospholipase C will directly activate PKC?

Practice: _________, when formed by phospholipase C, triggers the release of calcium from the endoplasmic reticulum?

Practice: In cells, epinephrine binding to the α-adrenergic receptor activates G αq. All of the following happen EXCEPT:

Practice: All G proteins are activated by GDP/GTP exchange (binding to GTP), but lose their activity when they hydrolyze GTP to GDP. However, different G proteins can have different roles. Which of the following is INCORRECT?

Practice: The reaction catalyzed by Phospholipase C can use all of the following EXCEPT: