Concept #1: Isoelectric Point of Amino Acids

Concept #2: Isoelectric Point of Amino Acids With Non-Ionizable R-Groups

Practice: Draw the structure of Leu and determine its pI. pK a1 = 9.6. pKa2 = 2.4.

a. 7.59                                          

b. 6.0

c. 3.91

d. 5.5

Practice: At any pH below the pI, the population of amino acids in solution with non-ionizable R-groups will have: