Introduction to Protein-Ligand Interactions
Protein-Ligand Equilibrium Constants
Protein-Ligand Fractional Saturation
Myoglobin vs. Hemoglobin
Heme Prosthetic Group
Hemoglobin Cooperativity
Hill Equation
Hill Plot
Hemoglobin Binding in Tissues & Lungs
Hemoglobin Carbonation & Protonation
Bohr Effect
BPG Regulation of Hemoglobin
Fetal Hemoglobin
Sickle Cell Anemia
Chymotrypsin's Catalytic Mechanism
Glycogen Phosphorylase
Liver vs Muscle Glycogen Phosphorylase
Motor Proteins
Skeletal Muscle Anatomy
Skeletal Muscle Contraction

Concept #1: Introduction to Protein-Ligand Interactions

Concept #2: Protein-Ligand Rate Constants

Practice: Which of the following rate law expressions represents a protein-ligand interaction at equilibrium?

Practice: Calculate the dissociation rate constant (kd) at equilibrium if [P] = 20 mM, [L] = 10 mM, [PL] = 5 mM, and the association rate constant (ka) = 100 mM-1s-1.