Ch. 12 - BiosignalingWorksheetSee all chapters
All Chapters
Ch. 1 - Introduction to Biochemistry
Ch. 2 - Water
Ch. 3 - Amino Acids
Ch. 4 - Protein Structure
Ch. 5 - Protein Techniques
Ch. 6 - Enzymes and Enzyme Kinetics
Ch. 7 - Enzyme Inhibition and Regulation
Ch. 8 - Protein Function
Ch. 9 - Carbohydrates
Ch. 10 - Lipids
Ch. 11 - Biological Membranes and Transport
Ch. 12 - Biosignaling
Clutch Review 1: Nucleic Acids, Lipids, & Membranes
Clutch Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Clutch Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism
Clutch Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Sections
Introduction to Biosignaling
G protein-Coupled Receptors
Stimulatory Adenylate Cyclase GPCR Signaling
cAMP & PKA
Inhibitory Adenylate Cyclase GPCR Signaling
Drugs & Toxins Affecting GPCR Signaling
Recap of Adenylate Cyclase GPCR Signaling
Phosphoinositide GPCR Signaling
PSP Secondary Messengers & PKC
Recap of Phosphoinositide Signaling
Receptor Tyrosine Kinases
Insulin
Insulin Receptor
Insulin Signaling on Glucose Metabolism
Recap Of Insulin Signaling in Glucose Metabolism
Insulin Signaling as a Growth Factor
Recap of Insulin Signaling As A Growth Factor
Recap of Insulin Signaling
Jak-Stat Signaling
Lipid Hormone Signaling
Summary of Biosignaling
Signaling Defects & Cancer

Concept #1: Insulin Receptor

Example #1: Insulin binds to a receptor that:

Practice: The insulin receptor is an example of a _______:

Concept #2: INSR Substrates (IRS)

Practice: Insulin binds to a receptor that:

I. Is coupled to a G protein.
II. Possesses tyrosine kinase activity.
III. Possesses serine/threonine phosphatase activity.
IV. Interacts with the adapter protein IRS-1.

Practice: Which of the following is TRUE concerning the interaction between the insulin receptor and IRS-1: