Hemoglobin Carbonation & Protonation

Practice: Which option best corresponds with the effect of CO₂ on hemoglobin’s O₂-binding?

Practice: Which statement is true about protons binding to hemoglobin?

Practice: Alkalemia is a disease associated with an abnormal increase in the pH of a patient’s blood due to rapid breathing (hyperventilation). How would alkalemia affect the oxygen binding affinity of the patient’s hemoglobin?

Practice: Choose all of the following molecules that, when bound, trigger hemoglobin’s transition from T to R state.