Sections
Enzymes
Enzyme-Substrate Complex
Lock and Key Vs. Induced Fit Models
Optimal Enzyme Conditions
Activation Energy
Types of Enzymes
Cofactor
Catalysis
Electrostatic and Metal Ion Catalysis
Covalent Catalysis
Reaction Rate
Enzyme Kinetics
Rate Constants and Rate Law
Reaction Orders
Rate Constant Units
Initial Velocity
Vmax Enzyme
Km Enzyme
Steady-State Conditions
Michaelis-Menten Assumptions
Michaelis-Menten Equation
Lineweaver-Burk Plot
Michaelis-Menten vs. Lineweaver-Burk Plots
Shifting Lineweaver-Burk Plots
Calculating Vmax
Calculating Km
Kcat
Specificity Constant

Concept #1: Formation of Enzyme-Substrate Complexes

Example #1: Appropriately label the arrows in the reaction energy diagram below using the provided terms.

Concept #2: Binding Energy

Practice: What can the binding energy (ΔGB) of an enzyme catalyzed reaction tell us?

Practice: Which is the best definition of binding energy regarding enzyme catalysis?

Practice: Which of the following is true of the binding energy derived from enzyme-substrate interactions?