Practice: Identify all the correct statements regarding the Bohr effect on hemoglobin.
i) The Bohr effect shifts the fractional O2 saturation curve to the right as pH decreases.
ii) The Bohr effect shifts the fractional O2 saturation curve to the right as pH increases.
iii) The Bohr effect favors O2 release in respiring tissues.
iv) O2 and H+ compete for the same binding site on hemoglobin.