Ch. 4 - Protein StructureWorksheetSee all chapters
All Chapters
Ch. 1 - Introduction to Biochemistry
Ch. 2 - Water
Ch. 3 - Amino Acids
Ch. 4 - Protein Structure
Ch. 5 - Protein Techniques
Ch. 6 - Enzymes and Enzyme Kinetics
Ch. 7 - Enzyme Inhibition and Regulation
Ch. 8 - Protein Function
Ch. 9 - Carbohydrates
Ch. 10 - Lipids
Ch. 11 - Biological Membranes and Transport
Ch. 12 - Biosignaling
Clutch Review 1: Nucleic Acids, Lipids, & Membranes
Clutch Review 2: Biosignaling, Glycolysis, Gluconeogenesis, & PP-Pathway
Clutch Review 3: Pyruvate & Fatty Acid Oxidation, Citric Acid Cycle, & Glycogen Metabolism
Clutch Review 4: Amino Acid Oxidation, Oxidative Phosphorylation, & Photophosphorylation
Sections
Peptide Bond
Primary Structure of Protein
Altering Primary Protein Structure
Drawing a Peptide
Determining Net Charge of a Peptide
Isoelectric Point of a Peptide
Approximating Protein Mass
Peptide Group
Ramachandran Plot
Atypical Ramachandran Plots
Alpha Helix
Alpha Helix Pitch and Rise
Alpha Helix Hydrogen Bonding
Alpha Helix Disruption
Beta Strand
Beta Sheet
Antiparallel and Parallel Beta Sheets
Beta Turns
Tertiary Structure of Protein
Protein Motifs and Domains
Denaturation
Anfinsen Experiment
Protein Folding
Chaperone Proteins
Quaternary Structure
Simple Vs. Conjugated Proteins
Fibrous and Globular Proteins

Concept #1: Antiparallel and Parallel Beta Sheets

Practice: Silk fibroin contains predominantly β sheet conformation. Which of the following is true regarding its β sheets?

Concept #2: Antiparallel and Parallel Beta Sheet Hydrogen Bonding

Practice: The diagram illustrates: 

Practice: The major reason that antiparallel β-sheets are more stable than parallel β-sheets is that the latter:

Practice: Which (phi, psi) pair of bond angles is closest to those of the residues shown in the figure below?

Practice: What type of β-sheet is presented in the figure below? Draw all hydrogen bonds between appropriate groups.

Practice: Draw a two-stranded antiparallel β-sheet with appropriate hydrogen bonding between the following peptides:                                   

1) L-A-D-Y.                   

2) G-A-G-A.