Sections
Diprotic Acids and Bases
Polyprotic Acids and Bases
Diprotic Buffers
Polyprotic Buffers
Principal Species
Isoelectric and Isoionic pH

Depending on the pH of the solution different forms of protic product can exist. 

Principal Species

Concept #1: By comparing the pH to the pKa value you can determine which form will predominate within a given solution. 

Example #1: What is the predominant form of the diprotic acid, methionine, at a pH equal to 4.18? Ka1 = 6.6 x 10-3 and Ka2 = 8.3 x 10-10.

Example #2: What is the predominant form of histidine at a pH equal to 8.00? pKa1 = 1.6, pKa2 = 5.97 and pKa3 = 9.28. 

Example #3: What is the second most predominant form in the previous question?